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目的 :了解我国艾滋病 (AIDS)患者的临床流行病学特点 ,自然病程及临床转归。方法 :汇集国内 6个地区的 4 82例AIDS患者的流行病学和临床资料 ,加以归纳总结。结果 :4 82例AIDS男女间的比例为 4∶1;其传播途径在云南、新疆主要为静脉注射毒品 ,河南为不洁献血和输血 ,而北京、上海、广州则主要为性途径传播 ;其性传播者的自然病程约为 8年 ,静脉注射毒品和经血感染者为 6年左右。临床症状以发热、消瘦、口腔和肺部感染等表现为主。常见的合并感染与文献报道类似。结论 :自 1985年发现第一例AIDS ,相当一部分人类免疫缺陷病毒 (HIV)感染者已进入AIDS期 ,本资料提示经血液途径感染者自然病程较经性途径感染者为短 ,我国HIV感染者中 70 .6%是静脉注射毒品者 ,提示及时预防感染、早期诊断 ,是我国HIV/AIDS综合防治的重要环节
Objective: To understand the clinical epidemiological characteristics, natural history and clinical outcome of AIDS patients in China. Methods: The epidemiological and clinical data of 4 82 AIDS patients in 6 regions of China were collected and summarized. Results: The ratio of 4 82 AIDS patients was 4: 1. The routes of transmission were in Yunnan and Xinjiang, mainly for intravenous drug use, Henan for unclean blood donation and blood transfusion, while Beijing, Shanghai and Guangzhou mainly for sexual transmission; Sexual transmission of natural course of about 8 years, intravenous drug and menstrual infection for about 6 years. Clinical symptoms with fever, weight loss, oral and pulmonary infections mainly performance. Common infection and reported in the literature similar. CONCLUSION: Since the first case of AIDS was found in 1985, a considerable number of people infected with human immunodeficiency virus (HIV) have entered the AIDS stage. The data suggest that the natural course of infection by the bloodstream pathogen is shorter than that by the sexual pathogen. HIV-infected people in China 70.6% were intravenous drug users, suggesting timely prevention of infection and early diagnosis are important links in the comprehensive prevention and treatment of HIV / AIDS in China