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[目的]探讨严重烧伤延迟复苏患者的液体复苏方法,提高烧伤休克复苏质量。[方法]将72例严重烧伤延迟复苏的患者按不同时期治疗措施的不同分成2组,即2000年1月～2004年12月(常规组)及2005年1月～2008年12月(综合组),进行比较分析。[结果]综合组休克纠正时间缩短,尿液转碱时间提前,伤后第1个24 h、第2个24 h的输液总量及尿量均明显增加。综合组BLA、BD、CK-MB、GPT、Cr、BUN等指标下降(P﹤0.01～0.05)。[结论]快速有效的综合复苏、细胞保护、抗氧化治疗、蛋白酶抑制剂、钙通道阻滞剂、抗炎治疗、早期肠道营养和保护性肺通气策略等构成的综合复苏策略能更加有效地提高严重烧伤延迟复苏的休克复苏质量。
[Objective] To explore the method of liquid resuscitation in patients with delayed resuscitation of severe burn and improve the quality of burn shock resuscitation. [Method] The 72 patients with severe delayed resuscitation were divided into two groups according to different treatment measures from January 2000 to December 2004 (routine group) and January 2005 to December 2008 (comprehensive group ), For comparative analysis. [Result] The time of correction of shock in the combined group was shortened, the time of excretion of urine was advanced, and the total amount of transfusion and urine volume in the first 24 h and the second 24 h after injury significantly increased. The index of BLA, BD, CK-MB, GPT, Cr, BUN in the comprehensive group decreased (P <0.01 ~ 0.05). [Conclusion] A comprehensive and effective recovery strategy, such as rapid and effective comprehensive recovery, cytoprotection, anti-oxidative therapy, protease inhibitors, calcium channel blockers, anti-inflammatory therapy, early gut nutrition and protective pulmonary ventilation strategies, Improve the quality of shock resuscitation with delayed resuscitation of severe burn.