论文部分内容阅读
血管内皮细胞脂质蓄积在肥胖者动脉粥样硬化的发病机理中起重要作用。我们以前的研究发现,α硫辛酸能激活AMP活化的蛋白激酶,减少肥胖大鼠骨骼肌细胞中脂质蓄积。为了观察α硫辛酸是否通过激活内皮细胞AMP活化的蛋白激酶来改善内皮功能障碍。我们用肥胖大鼠和对照大鼠做实验,观
Vascular endothelial cell lipid accumulation plays an important role in the pathogenesis of atherosclerosis in obese subjects. Our previous study found that alpha-lipoic acid activates AMP-activated protein kinase and reduces lipid accumulation in skeletal muscle cells in obese rats. To see whether alpha lipoic acid improves endothelial dysfunction by activating endothelial cell AMP-activated protein kinase. We experiment with obese rats and control rats