用扫描电镜观察体外培养新生大鼠小脑颗粒细胞的增殖、迁移和分化。发现颗粒细胞从种植片的边缘沿纤维束或神经胶质细胞向周围迁移。培养的时间愈长,迁移的距离愈远,细胞也愈接近成熟。细胞的突起从无到有,由单突发展到多突。提示体外培养的小脑颗粒细胞仍保留体内细胞的一些生物学特性。 Scanning electron microscopy was used to observe the proliferation, migration and differentiation of cultured rat cerebellar granule cells in vitro. Granulosa cells were found to migrate from the periphery of the implant along the fiber bundles or glial cells to the periphery. The longer the incubation time, the farther the migration distance, the closer the cells are to maturation. Protrusion of the cell from scratch, by the sudden development of multiple sudden sudden. Tip cultured in vitro cerebellar granule cells still retain some of the biological characteristics of cells in vivo.