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目的:了解运动试验ST段压低不同幅度患者的冠状动脉病变和临床特点,并探讨其相关性。方法:选取114例运动试验阳性和可疑阳性同时行冠状动脉造影的患者为研究对象,按ST段压低幅度分为0.5～0.9mm组、1.0～1.9mm组和≥2.0mm组,比较3组患者冠状动脉病变和临床特点。结果:3组患者间的性别、年龄、心绞痛、高血压、糖尿病和室壁运动障碍人数差异无统计学意义(P>0.05),但经皮冠状动脉介入治疗术后的患者人数差异有统计学意义(P=0.032);在冠状动脉病变数目、发生部位方面差异无统计学意义(P>0.05);3组患者间血管狭窄90%以上者差异有统计学意义(P=0.035)。经进一步Logistic回归分析发现,血管狭窄90%以上是ST段压低幅度的独立影响因素。结论:运动试验诱发的ST段压低幅度可间接反映冠状动脉病变狭窄程度,且血管狭窄90%以上是ST段压低幅度的独立影响因素。但ST段压低幅度不能反映冠状动脉病变数目和发生部位。
OBJECTIVE: To understand the coronary artery lesions and clinical features of patients with different ranges of ST-segment depression during exercise test and to explore its correlation. Methods: A total of 114 patients with positive and suspicious positive results of coronary angiography were enrolled in this study. Patients were divided into 0.5-0.9 mm group, 1.0-1.9 mm group and 2.0 mm group according to the ST segment depression. Coronary artery disease and clinical features. Results: There was no significant difference in gender, age, angina pectoris, hypertension, diabetes mellitus and wall motion disorder between the three groups (P> 0.05), but there was significant difference in the number of patients after percutaneous coronary intervention (P = 0.032). There was no significant difference in the number and location of coronary artery lesions between the two groups (P> 0.05). There was significant difference in the number of coronary artery stenosis between the three groups (P = 0.035). Logistic regression analysis showed that more than 90% of the vascular stenosis was the independent influencing factor of ST depression. Conclusion: The ST-segment depression induced by exercise test can indirectly reflect the degree of coronary artery stenosis, and more than 90% of the vascular stenosis is the independent factor of ST-segment depression. However, ST-segment depression can not reflect the number of coronary lesions and the site of occurrence.