Objective To approach on clinical value of serum procalcitonin(PCT)and C-reactive protein(CRP)in diagnosis of ulcerative colitis(UC).Methods The PCT and CRP levels in 120 UC patients and 20 healthy volunteers were measured.Results The levels of serum T PCT and CRP levels in active UC and catabolic UC were higher than control group[(1.56±0.36)vs(0.33±0.16)μg/L,(6.57±2.96)vs(0.33±0.16)μg/L,(6.78±3.85)vs(0.68±0.23)mg/L,(23.46±12.53)vs(0.68±0.23) Objective To approach on clinical value of serum procalcitonin (PCT) and C-reactive protein (CRP) in diagnosis of ulcerative colitis (UC). Methods The PCT and CRP levels in 120 UC patients and 20 healthy volunteers were measured. Results of the levels of serum T PCT and CRP levels in active UC and catabolic UC were higher than control group [(1.56 ± 0.36) vs (0.33 ± 0.16) μg / L, (6.57 ± 2.96) vs (0.33 ± 0.16) μg / L, ± 3.85) vs (0.68 ± 0.23) mg / L, (23.46 ± 12.53) vs (0.68 ± 0.23)