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目的观察比较芬太尼、氯胺酮辅助异丙酚静脉全麻用于人工流产术的麻醉效果。方法选择自愿接受全麻下人工流产术的孕妇90例,随机分为对照组(C组),芬太尼组(F组)、氯胺酮组(K组)三组,每组30例,C组仅给异丙酚,不给任何辅助药物,F组先予芬太尼1μg/kg静脉注射。K组先静脉注射氯胺酮0.3 mg/kg,然后各组均将2 mg/kg的异丙酚于60 s内静脉注射完毕,待睫毛反射消失后再即行人工流产操作,观察SBP、DBP、HR、SpO2,评价麻醉效果。结果三组异丙酚用药量,F组和K组用量明显少于C组,效果明显优于C组,SpO2与麻醉前相比,C组和F组差异有统计学意义,C组和F组呼吸抑制多于K组,但三组HR变化不明显,作用持续时间无明显差异。结论阈下剂量的氯胺酮辅助异丙酚静脉全麻用于人工流产术具有镇痛效果确切,术中呼吸循环系统功能基本稳定,清醒程度高,并发症少等优点。
Objective To compare the anesthetic effect of fentanyl and ketamine adjunct propofol intravenous anesthesia for induced abortion. Methods Ninety pregnant women who underwent voluntary abortion under general anesthesia were randomly divided into control group (C group), fentanyl group (K group), ketamine group (K group), 30 cases in each group, C group Only propofol, do not give any adjuvant drugs, F group fentanyl 1μg / kg intravenous injection. In group K, ketamine 0.3 mg / kg was injected intravenously. After that, 2 mg / kg of propofol was intravenously injected within 60 s in each group. When the eyelash reflex disappeared, the artificial abortion operation was performed. SBP, DBP, HR, SpO2, evaluate the effect of anesthesia. Results The dosage of propofol in three groups was significantly lower than that of group C in group F and group K, and the effect was better than that of group C. The difference was statistically significant between group C and group F, Group respiratory depression than the K group, but the three groups of HR did not change significantly, the duration of the role of no significant difference. Conclusion The subthreshold dose of ketamine adjuvant propofol intravenous anesthesia for abortion has the exact analgesic effect, intraoperative respiratory circulatory system is basically stable, high level of consciousness, fewer complications.