目的 :探讨炎症反应与冠心病 (CHD)之间的关系。方法 :10 1例CHD患者分为 3组 ,即稳定型心绞痛 (SAP)组 (19例 )、不稳定型心绞痛 (UAP)组 (33例 )和急性心肌梗死 (AMI)组 (49例 )。分别采用免疫浊度法及血细胞计数仪 ,检测外周血中的C 反应性蛋白 (CRP)水平及白细胞 (WBC)总数。 2 0例AMI死亡患者的心肌组织切片进行病理学检查。结果 :AMI和UAP组血中CRP的水平和WBC总数明显高于对照组 (P <0 .0 1)。病理学检查发现 ,AMI患者心肌中有大量白细胞浸润。结论 :CHD发生、发展有炎症反应的参与 ,检测血中的CRP和WBC可作为监测病情、预测冠心病危险性的常规指标之一 Objective: To investigate the relationship between inflammatory reaction and coronary heart disease (CHD). Methods: A total of 10 CHD patients were divided into 3 groups: stable angina pectoris (SAP) group (19 cases), unstable angina pectoris group (33 cases) and acute myocardial infarction group (49 cases). The level of C reactive protein (CRP) and the total number of white blood cells (WBC) in peripheral blood were detected by immunoturbidimetry and hematology. Myocardial tissue sections from 20 patients with AMI were pathologically examined. Results: The levels of CRP and WBC in AMI and UAP groups were significantly higher than those in control group (P <0.01). Pathological examination found that AMI patients have a large number of myocardial infiltration of leukocytes. Conclusion: The occurrence and development of CHD are involved in the development of inflammatory reaction. The detection of CRP and WBC in blood can be used as one of the routine indexes to monitor the disease and predict the risk of coronary heart disease