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目的:探讨上消化道重建术后空肠上段肠道菌群的种类、数量与感染并发症的关系。方法:前瞻性观察上消化道手术病人52例。分别于术中、术后第2天和第5天抽取病人空肠上段肠液,测定肠液菌群种类和菌落计数,同时检测病人血浆内毒素水平。结果:术中、术后第2和第5天无明显菌群失调及细菌移位发生(各菌种之间细菌菌落数比较,P>0.05)。术中、术后第2和第5天血浆内毒素水平无显著性差异(P>0.05)。结论:上消化道重建术后,无明显肠道菌群紊乱。
Objective: To investigate the relationship between the types and quantity of intestinal flora in the upper jejunum after upper gastrointestinal reconstruction and the complications of infection. Methods: Fifty-two cases of upper gastrointestinal surgery were prospectively observed. The patients’ jejunum intestinal juice was drawn intraoperatively, on the 2nd and 5th postoperative day respectively. The types of intestinal microflora and colony counts were determined, and the level of plasma endotoxin in the patients was also measured. Results: There was no obvious bacterial imbalance and bacterial translocation on the 2nd and 5th postoperative day (P> 0.05). There was no significant difference in plasma endotoxin levels between the two groups at postoperative day 2 and day 5 (P> 0.05). Conclusion: There is no obvious intestinal flora disturbance after upper gastrointestinal reconstruction.