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目的 研究煤烟与肺癌危险度的关系。方法 在甘肃陇东地区进行了一项肺癌病例 -对照流行病学研究。研究地区大部分人住在窑洞中 ,取暖和做饭使用煤和未经处理的生物燃料 (庄稼秸杆 ,木材 ,木棍和树枝 )。调查了在 1994年到 1998年期间诊断的 846名肺癌病人和根据人口调查资料随机确定的 1740名对照。结果 对居住时间最长的房间 ,室内用煤的肺癌病例与用生物燃料的肺癌病例相比 ,其比值比为 1 2 9(95 %置信限 :1 0 3 ,1 61) ,此值已对吸烟和社会经济状况进行了调整。肺癌危险度的增加与过去 3 0年中用煤的时间百分率有关 (P =0 0 2 )。结论 研究表明 ,在甘肃陇东农业地区 ,煤烟对肺癌危险度的增加起了重要作用。
Objective To study the relationship between the risk of soot and lung cancer. Methods A lung cancer case-control epidemiology study was conducted in Gansu Longdong area. Most people in the study area live in cave dwellings, heating and cooking coal and untreated biofuels (crop straws, wood, sticks and twigs). A total of 846 lung cancer patients diagnosed between 1994 and 1998 were surveyed and 1740 controls randomly selected from the census data. Results The odds ratio was 122 (95% confidence limit: 103, 161) for lung cancer cases in room-occupying coal and indoor biodiesel compared to lung cancer cases using biofuel for the longest period Smoking and socio-economic conditions were adjusted. The increased risk of lung cancer is related to the percentage of time spent on coal over the past 30 years (P = 0 0 2). Conclusions Research indicates that soot plays an important role in increasing the risk of lung cancer in Gansu agricultural areas of eastern Gansu Province.