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分析了1996年1月～1997年2月65例非妊娠肝内胆汁郁积症（ICP）孕妇，14例肝功能异常与20例ICP孕妇的血清甘腿酸（CG）与肝功能。结果表明，CG与丙氨酸转氨酶（ALT）的变化是一致的，ICP组CG与ALT值明显高于其他各组（P＜0．0），20例ICP患者100％CG值增高，85％ALT活性升高，提示以CG含量诊断ICP较ALT灵敏。CG超过正常值10倍时，出现重度瘙痒、黄疽以及胎儿窘迫的频率明显高于CG未超过10倍组，证明CG水平与疾病严重程度及胎儿预后有关。
Sixty-five pregnant women with non-pregnant intrahepatic cholestasis (ICP), 14 patients with abnormal liver function and 20 pregnant women with ICP were analyzed from January 1996 to February 1997 with serum CG and liver function. The results showed that the changes of CG and ALT were consistent, the CG and ALT values in ICP group were significantly higher than those in other groups (P <0.0), 100% CG values were increased in 20 patients with ICP, 85% ALT activity increased, suggesting that the ICP content of CG is more sensitive than ALT. The frequency of severe itching, jaundice and fetal distress was significantly higher than that of CG not more than 10-fold when CG exceeded 10 times of the normal value. It was proved that the level of CG was related to the severity of the disease and fetal prognosis.