论文部分内容阅读
本文用免疫荧光和免疫酶标方法研究慢性胃炎胃粘膜内抗体产生细胞的分布,探讨慢性胃炎与体液免疫反应的关系。选择浅表性胃炎24例,萎缩性胃炎29例。病人均经胃经检查,病理确诊。活检组织块用PBB冲洗,冷酒精固定处理,并作免疫荧光;双标记免疫荧光,免疫酶标染色,进行对照观察。结果表明:①慢性浅表性胃炎胃粘膜中,三种抗体产生细胞均增加,(P<0.01),但以IgM和IgA产生细胞为主。②萎缩性胃炎粘膜中,三种抗体产生细胞也增加,其中以IgG产生细胞增加为主。③萎缩性胃炎
In this study, the distribution of antibody-producing cells in the gastric mucosa of chronic gastritis was studied using immunofluorescence and immunoenzymatic labeling methods to investigate the relationship between chronic gastritis and humoral immune responses. There were 24 cases of superficial gastritis and 29 cases of atrophic gastritis. All patients were examined by gastric examination and confirmed by pathology. Biopsies were washed with PBB, fixed with cold alcohol, and immunofluorescence; double-labeled immunofluorescence, immunolabeling, and control observation. The results showed that: (1) In the chronic superficial gastritis, the three kinds of antibody-producing cells increased in the gastric mucosa (P<0.01), but mainly IgM and IgA-producing cells. 2 In the mucosa of atrophic gastritis, three kinds of antibody-producing cells also increased, of which mainly IgG-producing cells increased. 3 atrophic gastritis