OBJECTIVE:To investigate the antimicrobial activity,hemagglutination and phytotoxic activity of crude ethanolic and aqueous extracts of Seriphidium kurramense.METHODS:The extracts were analyzed by agar well diffusion assays against five bacterial species:Staphylococcus aureus (S.aureus),methicillin-resistant S.aureus,Escherichia coli,Klebsiella pneumoniae,Bacillus subtilis,and Salmonella typhi.The extracts were also screened against six fungal species-Aspergillus niger,Aspergillus flavus,Altaria solani,Rhizoctonia solani,Fusarium solani and Pleurotus florida-using the agar tube diffusion method.Additionally,hemagglutination and phytotoxic activities of the crude ethanolic and aqueous extracts were assessed.RESULTS:The crude ethanolic and aqueous extracts showed dose-dependent inhibition of the various tested fungal and bacterial strains.No hemagglutination activity was observed.Both the ethanolic and aqueous extracts showed dose-dependent phytotoxic activity toward Lemna minor.CONCLUSION:The crude ethanolic and aqueous extracts of Seriphidium kurramense possess good antimicrobial and phytotoxic activities,but no hemagglutination activity.