假卟啉症(Pseudoporphyria)主要表现为迟发性皮肤卟啉症(PCT)的皮肤发现,但在生物化学上无卟咻异常。某些药物如萘啶酸(nalidixic acid)、四环素和高剂量速尿可引起假卟啉症。作者报告5例萘普生(naproxen)并发的假卟啉症。5例病人(男1,女4)因关节炎、颈椎炎或背痛服萘普生后出现皮肤变脆、手背有大疱或水疱发生,其中3例病史5～6个月,余为15个月和3年,皮损均表现在暴露阳光的部位。血浆、尿、粪卟啉 Pseudoporphyria is mainly manifested as the skin finding of delayed-onset cutaneous porphyria (PCT), but not biochemically. Some drugs such as nalidixic acid, tetracycline, and high-dose furosemide can cause pseudoporphyrinosis. The authors report five cases of naproxen complicated pseudoporphyria. 5 patients (male 1, female 4) due to arthritis, cervical spondylosis or back pain naproxen skin becomes brittle, large blisters or blisters on the back of the hand, of which 3 cases of history of 5 to 6 months, the remaining 15 Months and 3 years, skin lesions are exposed in the exposed parts of the sun. Plasma, urine, coproporphyrin