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近年来由于临床上广泛应用抗菌素,病原菌抗药菌株明显增加,特別是金黄色葡萄球菌对青霉素的耐药率,国内不少地区报告已达到90%左右。其他药物的滥用,亦能引起耐药现象及不良反应。药物使用不当,不仅浪費人力物力,更重要的是可使致病菌产生耐药性,到必须用药时反失去其抑菌杀菌作用,甚至引起病人对药物的过敏,如在作青霉素、鏈霉素皮肤試驗时即曾发生过敏性休克和死亡。本文拟就基层单位合理用药问题,谈谈个人的体会。
In recent years, due to the widespread use of antibiotics in clinical practice, the number of drug-resistant strains of pathogens is significantly increased, especially the rate of drug resistance to penicillin in Staphylococcus aureus. In many areas in China, the reports have reached about 90%. Abuse of other drugs can also cause drug resistance and adverse reactions. Improper use of drugs, not only a waste of manpower and resources, but more importantly, the bacteria can produce resistance to the anti-bacterial bactericidal effect must be anti-drugs, or even cause the patient’s allergies to drugs, such as penicillin, streptomycin Suffering from skin tests that have occurred in anaphylactic shock and death. This article intends to make rational use of drugs at the grass-roots units to talk about personal experience.