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目的 应用Amplazter封堵器经皮顺行导管治疗动脉导管未闭并对其疗效进行评价。方法 全组 1 8例 ,男 8例 ,女 1 0例 ,平均年龄 6 .78± 4 .65(2 .5～ 33)岁 ,平均体重 2 6 .2± 1 1 .9(1 2 .4～ 55)kg。动脉导管未闭最窄处直径为 4 .86± 1 .97(2 .0～ 1 0 .0 )mm。经 6或 7F导管置入Amplazter封堵器 ,术后 1 0min行侧位降主动脉造影观察有无分流。术后 1天、1个月、6个月行超声心动图检查观察有无残余分流及动脉导管未闭再通。结果 所有病例均一次封堵成功 ,无任何并发症发生。术后 1 0min降主动脉造影示 3例有微至少量残余分流。术后 2 4h超声心动图均无残余分流。随访 1～ 6个月 ,均未发现有残余分流及再通。结论 应用Amplazter封堵器治疗直径达 1 0mm的动脉导管未闭是一种安全有效的介入方法 ,操作简便 ,成功率高 ,疗效可靠。
Objective To evaluate the curative effect of patent ductus arteriosus with Amplazter occluder and transcatheter arterial catheterization. Methods The whole group of 18 cases, 8 males and 10 females, average age 6 .78 ± 4 .65 (2.5 ~ 33) years old, average body weight 26.2 ± 1 1 .9 (12.4 ~ 55) kg. The diameter of the patent ductus arteriosus at the narrowest point was 4.86 ± 1 .97 (2.0-0.1.0 mm). After 6 or 7F catheters into Amplazter occluder, 10min postoperative descending aorta angiography with or without shunt. After 1 day, 1 month, 6 months underwent echocardiography to check for residual shunt and recanalization of patent ductus arteriosus. Results All cases were successfully blocked without any complications. At 10 min after descending aorta angiography showed a slight residual flow in 3 patients. There was no residual shunt at 24 h after echocardiography. All the patients were followed up for 1 ~ 6 months, no residual shunt and recanalization were found. Conclusion The application of Amplazter occluder in the treatment of patent ductus arteriosus with a diameter of 10 mm is a safe and effective interventional method. The operation is simple and convenient, the success rate is high and the curative effect is reliable.