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目的分析肺癌合并静脉血栓栓塞症(VTE)患者的临床特点及其预后。方法选取2013年2月至2015年2月肺癌合并VTE患者62例,其中肺血栓栓塞(PTE)36例,深静脉血栓(DVT)26例。均采用溶栓+抗凝或单纯抗凝进行治疗,观察分析肺癌合并VTE患者的临床特点及预后。结果 44例接受化疗后采用溶栓+抗凝的VTE患者中,30例有效,9例无效自动出院,5例死亡,有效率为68.18%。18例单纯抗凝治疗者中,11例有效,5例无效自动出院,2例死亡,有效率为61.11%。所有患者住院期间有效41例,有效率为66.13%;死亡7例,病死率为11.29%。结论 VTE是肺癌的主要并发症之一,其主要临床特点表现为胸闷气短、胸痛、咯血、呼吸急促、咳嗽以及胸腔积液等症状,及时确诊加上有效的治疗措施可缓解患者的病情,改善临床症状。
Objective To analyze the clinical characteristics and prognosis of patients with lung cancer complicated with venous thromboembolism (VTE). Methods From February 2013 to February 2015, 62 patients with lung cancer complicated with VTE were selected, including 36 patients with pulmonary thromboembolism (PTE) and 26 patients with deep venous thrombosis (DVT). All cases were treated with thrombolysis plus anticoagulation or anticoagulation alone. The clinical features and prognosis of patients with lung cancer complicated with VTE were observed and analyzed. Results Of the 44 VTE patients treated with thrombolytic therapy and anticoagulation therapy, 30 were effective, 9 were ineffectively discharged, 5 were dead, and the effective rate was 68.18%. Of the 18 patients treated with anticoagulant therapy, 11 were effective, 5 were ineffectively discharged, and 2 died, with an effective rate of 61.11%. All patients were effective during hospitalization in 41 cases, the effective rate was 66.13%; 7 died, the mortality rate was 11.29%. Conclusions VTE is one of the major complications of lung cancer. Its main clinical features are chest tightness, shortness of breath, chest pain, hemoptysis, shortness of breath, cough and pleural effusion. The timely diagnosis and effective treatment can relieve the patient’s condition and improve Clinical symptoms.