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本研究对35岁以上正常人群进行普查筛检,以期发现早期大肠癌。7603例受检者中试纸法粪便隐血试验的阳性率为12.9％(986例),应用我院自制的羊抗人血红蛋白抗体进行免疫法复检的阳性率仅为1.4％(108例)。90例免疫法阳性者接受纤维结肠镜检查,发现大肠病变23例(0.3％)。本研究结果表明,进行大范围普查筛检,可以提高病变检出率,并能检出亚临床状态的大肠癌前病变,进行防治观察。本研究采用的筛检法简便易行,经济实效。
This study screened normal people over the age of 35 for screening for early colorectal cancer. The positive rate of fecal occult blood test in 7603 subjects was 12.9% (986 cases), and the positive rate of using goat anti-human hemoglobin antibody made in our hospital was only 1.4% (108 cases). Ninety cases of immunologically positive patients underwent colonoscopy and found 23 cases (0.3%) of colorectal lesions. The results of this study indicate that conducting a large-scale census screening can increase the detection rate of lesions, detect subclinical precancerous lesions of the colorectal cancer, and conduct preventive and therapeutic observations. The screening method used in this study is simple and economical.