浆果样动脉瘤破裂是自发性蛛网膜下腔出血(SAH)最常见的原因,虽然近年来内外科治疗已有明显的进展,因一般只有在动脉瘤破裂后方获诊断而延迟治疗。因此,数十年来死亡率及致残率仍甚高,关键问题是未能预测动脉瘤的发展与破裂的危险因素。作者于1959～1984年在尸检中对颅内浆果样动脉瘤发生及其破裂的危险因素进行了研究(包括年龄、种族、性别及潜在性疾病)。对既往有高血压(舒张压>110mmHg)、吸烟2包/日以上持续20年或更长者、饮酒1品托/日以上、动脉粥样硬化伴溃疡性斑块、动脉管腔狭窄达70%以上与过度扩张者均施行了临床与病理研究。170例浆果样动脉瘤尸检,男67例、女103例,平均年龄52.4±1.1岁。破裂 Berry-like aneurysm rupture is the most common cause of spontaneous subarachnoid hemorrhage (SAH). Although there have been significant advances in endosurgical treatment in recent years, treatment is generally delayed only after aneurysm rupture has been diagnosed. As a result, mortality and morbidity have remained high for decades, and the key issue is the failure to predict the risk of aneurysm development and rupture. Authors examined the risk factors for the occurrence and rupture of intracranial berry-like aneurysms (including age, race, gender, and underlying disease) at autopsy from 1959 to 1984. On the previous high blood pressure (diastolic blood pressure> 110mmHg), smoking more than 2 packs / day for 20 years or longer, drinking more than 1 pint / day, atherosclerosis with ulcerative plaque, arterial stenosis up to 70 More than% of patients with over-dilation were performed clinical and pathological studies. 170 cases of berry-like aneurysm necropsy, 67 males and 103 females, with an average age of 52.4 ± 1.1 years. rupture