作者曾推测母亲的抗Ro(SS-A)抗体可能是同SLE遗传倾向有关的一种免疫学标志.为验证这一假设,作者检查了71例SLE儿童的188名一级亲属的血清.71例患者年龄<18岁,均符合ARA 1982年修订的SLE诊断标准.188名一级亲属中有66名母亲、38名父亲、42名兄弟和42名姐妹,他们均无症状, The authors speculated that maternal anti-Ro (SS-A) antibodies may be an immunological hallmark related to genetic predisposition to SLE.To validate this hypothesis, the authors examined sera from 188 first-degree relatives of 71 SLE children.71 The patients, aged <18 years, all met the diagnostic criteria for SLE as revised by ARA in 1982. There were 66 mothers, 38 fathers, 42 brothers and 42 sisters in 188 first-degree relatives who were asymptomatic,