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目的分析妊娠合并麻疹患者的临床特征及妊娠结局,以期为临床及时诊治提供参考。方法采用回顾性研究方法,选取2014年9月至2016年12月收治的妊娠合并麻疹患者47例为观察组,另选同期非妊娠麻疹患者47例为对照组。对比两组患者临床表现以及实验室检查结果,并分析观察组患者的妊娠结局情况。结果观察组患者均存在发热、上呼吸道症状、皮疹等麻疹临床特征性表现,但其发生率与对照组比较均无统计学差异(P均>0.05)。观察组血钾降低、肌酸激酶升高、乳酸脱氧酶升高发生率分别为34.04%、74.47%、51.06%,均高于对照组的6.38%、12.77%和10.64%,差异有统计学意义(P均<0.01)。经对症治疗后,观察组27例早中期妊娠患者中,流产及死胎发生率为18.52%(5/27);20例晚期妊娠患者宫内窘迫中,早产发生率为5.00%(1/20),剖宫产术率为35.00%(7/20),新生儿麻疹发生率为10.00%(2/20)。结论妊娠合并麻疹患者的病情较为严重,且对妊娠结局会造成不良影响,应予以及时诊断和治疗,注意预防和控制并发症,以保证母婴健康。
Objective To analyze the clinical features and pregnancy outcome of measles patients with pregnancy in order to provide reference for clinical diagnosis and treatment. Methods A retrospective study was conducted. Forty-seven pregnant women with measles in pregnancy from September 2014 to December 2016 were selected as the observation group and 47 non-pregnant measles patients as the control group. The clinical manifestations and laboratory findings of the two groups were compared and the outcome of pregnancy in the observation group was analyzed. Results All patients in the observation group had clinical manifestations of fever, upper respiratory symptoms and rash. However, the incidence of measles was not significantly different from that of the control group (all P> 0.05). The observation group, the serum potassium decreased, creatine kinase increased lactate dehydrogenase increased incidence rates were 34.04%, 74.47%, 51.06%, were higher than the control group 6.38%, 12.77% and 10.64%, the difference was statistically significant (P <0.01). After symptomatic treatment, the incidence of miscarriage and stillbirth was 27.52% (5/27) in 27 cases of early pregnancy in the observation group. The incidence of preterm birth was 5.00% (1/20) in 20 cases of late pregnancy with intrauterine distress. , Cesarean section rate was 35.00% (7/20), neonatal measles incidence was 10.00% (2/20). Conclusions Pregnancy complicated with measles is more serious and causes adverse effects on pregnancy outcome. It should be diagnosed and treated promptly to prevent and control complications and ensure the health of mother and baby.