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自Avellis(1900)首次将喉上神经痛作为一种特发性综合征报道以来,很多学者均认为此病疼痛部位限局于一侧喉部,尚无发生于双侧的报告。作者们对1例出现发作性限局于双侧甲状软骨上部的疼痛作了分析。此患者疼痛呈发作性,部位恒定,持续数秒至数分钟,可因咳嗽、吞咽而诱发。神经系统检查无阳性发现。食管造影、胸片、直接喉镜、气管镜、食管镜、甲状腺活体、细胞学与细菌培养等检查均无异常,诊断为双侧喉上神经痛,给与卡马西平[carbamazepine,商品名痛可定(Tegretol)]每日200mg,以后逐增至每日1200mg,3周后疼痛消失,随访9个月无复发。
Since Avellis (1900) first reported laryngeal neuralgia as an idiopathic syndrome, many scholars believe that pain is limited to one side of the throat and no bilateral reports have been reported. The authors analyzed the onset of paroxysmal nociceptive pain in the upper part of bilateral thyroid cartilage in one patient. This patient’s pain was episodic, site constant for several seconds to minutes, can be caused by coughing, swallowing. No positive neurological examination found. Esophageal angiography, chest radiography, direct laryngoscopy, bronchoscopy, esophagoscopy, thyroid live, cytology and bacterial culture examination were normal, diagnosis of bilateral laryngeal neuralgia, carbamazepine [carbamazepine Tegretol] daily 200mg, later increased to 1200mg daily, 3 weeks after the pain disappeared, followed up for 9 months without recurrence.