目的研究济南市区成人每日人均铜(Cu)、锰(Mn)摄入量并探讨血清铜(SCu)和血清锰(SMn)含量的参考值范围。方法于2007年8月—2008年1月,以1005位济南市区健康成人作为调查对象,采用七天膳食摄入表法进行每人每日Cu和Mn摄入量调查;采用微波消解-原子吸收分光光度法检测其SCu和SMn含量。结果济南市区成人每日人均Cu摄入量为1.78mg,Mn摄入量为4.21mg。男性Cu摄入量高于女性(P<0.05)。年龄因素对人均每日Cu和Mn摄入量没有显著影响。济南市区成人SCu含量为(0.91±0.26)mg/L,参考值范围(P2.5～P97.5)为0.38～1.37mg/L;SMn含量为(7.04±3.19)μg/L,参考值范围(P2.5～P97.5)为3.54～15.56μg/L。性别、年龄因素对SMn含量没有显著影响。女性SCu含量高于男性(P<0.05)。SCu含量随年龄增长而增加(r=0.14,P<0.01),男性略明显(r=0.18,P<0.01)。结论本调查可以初步确定济南市区成人SCu和SMn的参考值范围。济南市区成人人均每日Cu摄入量低于我国成人Cu适宜摄入量(AI,2mg/d),而Mn则高于AI(3.5mg/d)。 Objective To study the per capita daily intake of copper (Cu) and manganese (Mn) in adults in Jinan city and to explore the reference value range of serum copper (SCu) and serum manganese (SMn) content. Methods From August 2007 to January 2008, 1005 healthy adults in Jinan City were investigated. The diet intake of seven days was used to investigate the intake of Cu and Mn per person per day. Microwave digestion - atomic absorption Spectrophotometric determination of SCu and SMn content. Results Daily intake of Cu per capita in urban area of ​​Jinan was 1.78 mg and Mn intake was 4.21 mg. Male Cu intake was higher than female (P <0.05). Age factors have no significant effect on daily Cu and Mn intake per person. The SCu content in urban area of ​​Jinan was (0.91 ± 0.26) mg / L, the reference range (P2.5 ~ P97.5) was 0.38 ~ 1.37 mg / L, the content of SMn was (7.04 ± 3.19) μg / L, The range (P2.5 ~ P97.5) was 3.54 ~ 15.56μg / L. Sex and age had no significant effect on SMn content. Female SCu content was higher than men (P <0.05). The SCu content increased with age (r = 0.14, P <0.01), while the male was slightly (r = 0.18, P <0.01). Conclusion The survey can initially determine the reference range of adult SCu and SMn in Jinan. The per capita daily intake of Cu in urban area of ​​Jinan is lower than that of adult Chinese (AI, 2mg / d), while that of Mn is higher than that of AI (3.5mg / d).