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基因打靶是近十年来发展起来的分子生物学技术,此项技术的应用和发展为人们在整体水平研究基因的功能及其调控、建章人类疾病动物模型和发展基因疗法提供了可靠的手段。本文综述了基因打靶技术的概况以及其在眼科疾病研究中的应用。
Gene targeting is a molecular biological technique developed in recent ten years. The application and development of this technology provide a reliable means for people to study the function and regulation of genes at the whole level, establish animal models of human diseases and develop gene therapy. This article reviews the overview of gene targeting technology and its application in the research of ophthalmology diseases.