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5 -氟尿嘧啶 (5—ＦＵ)是第一个根据一定设想而合成的抗代谢药 ,是临床上应用最广的抗肿瘤类药物之一 ,它是通过防止嘧啶类核苷酸的形成而干扰ＤＮＡ的合成来杀伤癌细胞 ,临床上主要用于治疗乳腺癌、消化道癌肿、卵巢癌和原发性支气管肺腺癌等。特别是在治疗消化道肿瘤方面 ,5
5-Fluorouracil (5-FU) is the first anabolic agent synthesized according to certain assumptions. It is one of the most widely used anti-tumor drugs in clinical practice and it interferes with DNA by preventing the formation of pyrimidine nucleotides Of the synthesis to kill cancer cells, clinically used mainly for the treatment of breast cancer, gastrointestinal cancer, ovarian cancer and primary bronchial adenocarcinoma. Especially in the treatment of gastrointestinal cancer, 5