慢性阻塞性肺疾病(chron ic obstructive pu lm onary d is-ease,COPD)是一种可以预防、可以治疗的疾病,以不完全可逆的气流受限为特点,气流受限常呈进行性加重,且多与肺部对有害颗粒或气体,主要是吸烟的异常炎症反应有关。虽然COPD累及肺,但也可以引起显著的全身效应[1,2]。目 Chronic obstructive pulmonary disease (COPD) is a preventable and treatable disorder characterized by incompletely reversible airflow limitation. The airflow limitation is often progressively aggravated, And more with the lungs of harmful particles or gases, mainly smoking, the abnormal inflammatory response. Although COPD affects the lungs, it can also cause significant systemic effects [1,2]. Head