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目的:探析糖尿病肾病(diabetic nephropathy,DN)患者早期诊断意义。方法:将2015年2月~2017年2月我院诊治的75例DN患者纳入观察组,选取同期参与体检的80例健康自愿者纳入对比组,均接受生化检测,对比两组C反应蛋白(CPR)、尿蛋白/尿肌酐(UALB/Cr)、视黄醇结合蛋白(RBP)、血胱抑素C(Cys C)等指标。结果:通过测定,观察组的CPR、UALB/Cr、RBP及Cys C指标均高于对比组,差异有统计意义(P<0.05);对于DN早期诊断联合检验的阳性率最高(P<0.05)。结论:DN患者相关生化指标水平均高于健康人群,是早期诊断的主要依据,且建议采取联合检测,有较高阳性检出率。
Objective: To investigate the significance of early diagnosis of diabetic nephropathy (DN). Methods: From July 2015 to February 2017, 75 patients with DN who were diagnosed and treated in our hospital were enrolled into the observation group. Eighty healthy volunteers who participated in the physical examinations in the same period were enrolled in the control group. All of them were biochemically tested. The levels of C-reactive protein CPR, UALB / RB, RBP, Cys C and so on. Results: The indexes of CPR, UALB / Cr, RBP and Cys C in the observation group were higher than those in the control group (P <0.05), and the positive rate of DN combined with early diagnosis was the highest (P <0.05) . Conclusion: The biochemical indexes in patients with DN are higher than those in healthy people, which is the main basis for early diagnosis. It is recommended to take joint examination and have a higher positive detection rate.