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目的评估肾动脉支架术后再狭窄的发生及肾功能及血压的改变。方法对135 例单侧或双侧肾动脉明显狭窄(管腔内径减少≥70％)的患者行肾动脉支架置入术(PTRAS),术后行肾动脉造影、血压及血肌酐(Scr)的随访观察。结果 135例患者植入147枚支架均获成功。术后肾动脉造影随访率70％,平均随访时间为(7．2±5．6)月,再狭窄率为7．4％。血压及肾功能随访率为95％,平均随访时间(22±6)月,随访患者的收缩压与舒张压均明显下降,分别为 [(172±23)比(159±20)mm Hg,P<0．05,(93±16)比(85±13)mm Hg,P<0．05]。但术后12个月及24个月Scr和GFR与术前比较无显著性差异。结论肾动脉支架置入术后的再狭窄率较低,PTRAS有助于患者的血压控制。
Objective To evaluate the occurrence of restenosis after renal artery stenting and the changes of renal function and blood pressure. Methods 135 patients with unilateral or bilateral renal artery stenosis (reduction of lumen diameter ≥70%) underwent renal artery stenting (PTRAS), postoperative renal artery angiography, blood pressure and serum creatinine (Scr) Follow-up observation. Results 135 patients were implanted 147 scaffolds were successful. The follow-up rate of renal artery angiography was 70%. The mean follow-up time was (7.2 ± 5.6) months and the rate of restenosis was 7.4%. The follow-up rates of blood pressure and renal function were 95% and the average follow-up time was 22 ± 6 months. The systolic and diastolic blood pressure were significantly decreased in follow-up patients, which were respectively (172 ± 23) and (159 ± 20) mm Hg <0.05, (93 ± 16) vs (85 ± 13) mm Hg, P <0.05]. However, there was no significant difference in the Scr and GFR at 12 and 24 months after operation compared with that before operation. Conclusions The rate of restenosis after renal artery stenting is relatively low. PTRAS is helpful for the control of blood pressure in patients.