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作者发现游离胆固醇与胆固醇酯的比值较游离胆固醇与总胆固醇之比值能更好地反映生理状态。同时发现,疾病时有些比值超出了正常范围,因而促使作者研究异常的比值与心脏病,癌症以及其它疾病之间可能有的关系。标本用空腹血清。游离胆固醇与胆固醇酯的测定用气液层析法。实验期间曾用不同的化学方法(其中包括全自动酶学法)测定总胆固醇。每次更换化学方法时,均测定了气液层析法与化学法之间的相关性。总胆固醇与游离胆固醇之差即为胆固醇酯。作者检测了38个健康人,年龄为20至60岁。其中25名女性,13名男性。总胆固醇的平均值和标准差为每100毫升195±36毫克。游离胆固醇为53±10毫克,胆固醇酯为142±26毫克。游离
The authors found that the ratio of free cholesterol to cholesteryl ester ratio of free cholesterol to total cholesterol can better reflect the physiological status. At the same time, it was found that some ratios at the time of the disease were outside the normal range, prompting the authors to investigate the possible relationship between the abnormal ratio and heart disease, cancer and other diseases. Specimens with fasting serum. Determination of free cholesterol and cholesterol esters by gas-liquid chromatography. During the experiment, different chemistries (including fully automated enzymatic assays) were used to determine total cholesterol. Each time the chemical method is changed, the correlation between the gas-liquid chromatography and the chemical method is determined. The difference between total cholesterol and free cholesterol is cholesterol ester. The author tested 38 healthy people, aged 20 to 60 years. 25 of them women and 13 men. The mean and standard deviation of total cholesterol was 195 ± 36 milligrams per 100 milliliters. 53 ± 10 mg free cholesterol and 142 ± 26 mg cholesterol ester. free