肾上腺皮质激素作为一种抑制免疫反应的药物已广泛应用于儿科临床,但必须注意到其对免疫功能的广泛和过度抑制作用。本文实验结果表明,激素可抑制巨噬细胞的吞噬功能、总补体活性、淋巴细胞对特异抗原的免疫反应,以及减少血清球蛋白和使胸腺、脾脏缩小等作用。随着激素剂量的增加,抑制作用有增强的趋势。 Corticosteroids, as a drug that inhibits the immune response, have been widely used in pediatric clinics, but its widespread and over-suppressive effects on immune function must be noted. The experimental results show that the hormones can inhibit the phagocytosis of macrophages, the total complement activity, the immune response of lymphocytes to specific antigens, the reduction of serum globulin and the reduction of thymus and spleen. With the increase of hormone dose, inhibition has an increasing trend.