先天性巨结肠症的发病原理尚未完全阐明,治疗则以外科手术为主,近年来用中西医结合治疗取得较好的效果。为了进一步研究所用中药(主要是人参)的疗效,我们对9例病儿的肠管作了体外药理实验。作为参考也对正常大鼠直肠进行体外实验。鉴于肠道嘌呤能神经的提法日益受到重视,因此也研究了三磷酸腺甙等药物对病儿肠管运动的影响。 The pathogenesis of congenital Hirschsprung’s disease has not yet been fully elucidated. The treatment is based on surgery. In recent years, the combination of Chinese and Western medicine has achieved good results. In order to further study the efficacy of traditional Chinese medicine (mainly ginseng), we conducted in vitro pharmacological experiments on the intestinal tract of 9 sick children. As a reference, normal rat rectum was also tested in vitro. In view of the increasing attention paid to the purine-nervous nerves of the intestine, the effects of adenosine triphosphate and other drugs on intestinal motility in sick children have also been studied.