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作者用泼尼松、柳氮磺胺吡啶、可乐定和安慰剂对45名溃疡性结肠炎(UC)病人进行了为期30周的双盲法研究。在随访至少一年后进行公开评价,发现可乐定和泼尼松都是治疗溃疡性结肠炎的有效药物。两药都优于柳氮磺胺吡啶,可乐定的疗效优于泼尼松。将45名UC病人(男20人,女25人,年龄17~51岁,病程1~23年)随机分三组,每组15人。各组病人按
The authors conducted a 30-week double-blind study of 45 ulcerative colitis (UC) patients with prednisone, sulfasalazine, clonidine and placebo. After a follow-up of at least one year after a public evaluation, clonidine and prednisone were found to be effective for the treatment of ulcerative colitis. Both drugs are superior to sulfasalazine, the effect of clonidine is better than prednisone. Forty-five UC patients (20 males and 25 females, aged from 17 to 51 years and with a duration of 1 to 23 years) were randomly divided into three groups of 15. According to each group of patients