抗菌药物的正确应用,不仅取决于对抗菌谱的了解,而且还取决于抗菌药物在感染部位能否达到抑菌或杀菌浓度。如果剂量太小、给药间隔过长、疗程太短、给药途径不当,均可造成抗菌药物治疗失效。笔者结合抗菌药物类型特点,以药效学理论为基础,论述抗菌药物的合理应用。 The correct application of antibacterial drugs, not only depends on the understanding of antimicrobial spectrum, but also depends on the antimicrobial drugs can reach the site of inhibition of bacteriostatic or bactericidal concentration. If the dose is too small, medication interval is too long, the course is too short, improper route of administration, can cause antimicrobial treatment failure. Based on the characteristics of antibacterials, the author discusses the rational application of antibacterials based on pharmacodynamics theory.