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哮喘和慢性阻塞性肺病是最常见的阻塞性气道疾病,主要表现为整个呼吸道的慢性炎症,研究显示在部分患者中,尤其是老年患者中哮喘和慢阻肺是可以发生重叠的,称之为哮喘-慢性阻塞性肺病重叠综合征(ACOS).尽管ACOS的发病率较高,但人们对它的认识却并不充分,尤其是在相关的临床实验中哮喘和慢阻肺多是互为对照组进行研究的.而近年来,随着对慢阻肺表型研究的深入,学者们对ACOS这一同时具有哮喘和慢阻肺的临床表现但又与之有所区别的疾病引起了重视并进行了一系列的研究.“,”Asthma and chronic obstructive pulmonary disease (COPD) are the most common obstructive airway diseases,mainly manifested with chronic inflammation affecting the whole respiratory tract.Some studies have shown that two diseases can appeared at the same time in partly patients,especially in elderly patients,known as asthma-chronic obstructive pulmonary disease overlap syndrome (ACOS).Although the incidence of ACOS is high,but it is not well recognized,especially in relevant clinical trial,patients with asthma and COPD are often divided in the control group to make comparison.However,in recent years,with in-depth research about phenotype of COPD,ACOS as a new disease that has clinical manifestations of asthma and COPD attracted our great attention and promoted a series of furthermore studies.