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作者用单因素分析，多元线性回归和多元逐步回归分析探讨了５４例骨肉瘤患者影响预后的因素。结果表明：肿瘤细胞核ＤＮＡ倍体水平、Ｘ线分级和外科分期是影响患者预后的主要因素：肿瘤部位、肿瘤最大径和以Ｓ期细胞百分数、增殖指数及核仁组成区嗜银蛋白染色表示的肿瘤细胞增殖活性对患者预后具有限的影响。患者年龄、性别、症状持续时间、肿瘤Ｘ线分型和病理分型则与生存率无关。
The authors used univariate analysis, multiple linear regression, and multiple stepwise regression analysis to explore the factors that affected prognosis in 54 patients with osteosarcoma. The results showed that nuclear DNA ploidy, X-ray grading and surgical staging of tumor cells were the main factors affecting the prognosis of the patients: tumor site, tumor maximal diameter and percentage of cells in S phase, proliferation index, and nucleolar protein staining The proliferation activity of tumor cells has a limited effect on the prognosis of patients. The patient’s age, gender, duration of symptoms, tumor X-ray type, and histological type were not associated with survival.