[目的]了解高州市外观健康犬只狂犬病病毒携带情况和人群狂犬病暴露与处置情况,为提出狂犬病防制对策提供依据。[方法]收集2007年高州市犬只饲养与动物伤人资料,对2008年高州市某乡小学205名学生家长进行狂犬病知识与犬伤情况问卷调查,2008年7～9月在市场采集健康犬脑和及唾液腺检测狂犬病病毒。[结果]高州市2007年动物伤人12029例,其中被犬所伤者占80.46%。调查205人,85.37%听说过狂犬病,其中66.34%知道狂犬病是被动物伤所致;61.46%的家里养犬。检测200只犬的标本,均为狂犬病病毒阴性。[结论]高州市家养犬只数量多,犬伤暴露状况严峻,居民狂犬病相关知识知晓率不高,尚未发现携带狂犬病病毒的犬只。 [Objective] To understand the appearance and appearance of rabies in healthy dogs in Gaozhou and the population exposure and treatment of rabies, so as to provide basis for the prevention and control of rabies. [Methods] The data of dog breeding and animal wounding in Gaozhou City in 2007 were collected. A questionnaire survey was conducted on the knowledge of rabies and dog injury in 205 pupils in a rural elementary school in Gaozhou City in 2008. From July to September 2008, healthy dogs Brain and salivary gland detection of rabies virus. [Results] In Gaozhou, animals were injured in 12,029 animals in 2007, of which 80.46% were injured by dogs. Survey 205 people, 85.37% heard of rabies, of which 66.34% knew that rabies was caused by animal injuries; 61.46% of domestic dogs. Samples from 200 dogs were negative for rabies virus. [Conclusion] The number of domestic dogs in Gaozhou was high, the dog exposure was severe, and the awareness rate of resident rabies related knowledge was not high. No rabies carrying rabies virus was found.