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目的探讨肝癌介入治疗的合理模式。方法回顾性总结1000例以不同方式进行介入治疗的肝癌病例资料,通过分析其病理、生化、影像及生存率等临床因素,比较各种治疗方式的价值及优缺点结果经导管节段性肝动脉栓塞化疗(S-TOCE)与常规肝动脉注射碘油抗癌药混悬剂栓塞化疗(C-TOCE)比较,前者对肿瘤的杀伤作用大,对非癌肝组织的损害较C-TOCE轻,生存率优于C-TOCE;经皮无水酒精注射术(PEI)联合栓塞治疗可起到杀死残余癌灶的作用,对非癌肝组织未造成明显损害,生存率较单纯栓塞明显提高。对肝癌的各种并发症采取不同方式的介入治疗,能不同程度地改善患者生存质量或提高生存率。结论肝癌的介入治疗应根据肿瘤大小和类型选择/不同的介入治疗方式;对肝癌的各种并发症采取积极的介入治疗是有效和必要的。
Objective To investigate the reasonable mode of interventional therapy for liver cancer. Methods The clinical data of 1000 cases of HCC with interventional treatment were retrospectively reviewed. The clinical value of various treatment methods were compared by clinical factors such as pathology, biochemistry, imaging and survival rate. Embolization chemotherapy (S-TOCE) and conventional hepatic artery injection of lipiodol anticancer drug suspension embolization chemotherapy (C-TOCE), the former has a large role in tumor killing, non-cancerous liver tissue damage than C-TOCE light, Survival rate is better than C-TOCE; percutaneous ethanol injection (PEI) combined embolization can kill the residual foci, the non-cancerous liver tissue did not cause significant damage, the survival rate was significantly improved compared with simple embolization. Various complications of liver cancer intervention in different ways, to varying degrees, improve patient quality of life or improve survival. Conclusion Interventional treatment of hepatocellular carcinoma should be based on the size and type of tumor selected / different interventions; positive interventional treatment of various complications of liver cancer is effective and necessary.