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目的:通过分析武汉地区34家医院抗真菌药的用药数据,了解该地区该类药物的用药现状和发展趋势。方法:对武汉地区医院2012~2014年抗真菌药的用药金额、市场占有率、用药频度(DDDs)及限定日费用(DDC)等进行统计分析。结果:2012~2014年武汉地区抗真菌药销售总金额及其增长率均逐年增加。其中吡咯类抗真菌药销售金额最高,伏立康唑的销售金额3年均位居第一,硝呋太尔制霉菌素栓和克霉唑阴道片的DDDs一直位于前两位。结论:武汉地区抗真菌药市场增长趋势显著,消费结构较为稳定。应加强对抗真菌药的应用评价工作,临床应合理使用抗真菌药,减缓或避免耐药菌的扩散。
Objective: To analyze the medication status and development trend of antifungal drugs in 34 hospitals in Wuhan area. Methods: Statistical analysis was conducted on the amount of antifungal drug, market share, DDDs and DDC between 2012 and 2014 in Wuhan district hospitals. Results: The total amount of antifungal drugs sold in Wuhan in 2012 and 2014 and its growth rate increased year by year. Among them, the sales amount of pyrrole antifungal drugs was the highest, voriconazole sales amount topped the first place for three years, and nifuratel’s nystatin suppository and clotrimazole vaginal tablets DDDs were always in the first two places. Conclusion: The antifungal drug market in Wuhan shows a significant growth trend and the consumption structure is relatively stable. Should strengthen the evaluation of the application of antifungal agents, clinical use of antifungal agents should be reasonable to slow or prevent the spread of resistant bacteria.