【摘 要】
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目的:探讨在2型糖尿病患者中早期使用胰岛素治疗对其胰岛β细胞功能的保护作用.方法:将近年于我院内分泌门诊及住院部诊治的73例初诊2型糖尿病患者纳入研究.根据数字随机法分
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目的:探讨在2型糖尿病患者中早期使用胰岛素治疗对其胰岛β细胞功能的保护作用.方法:将近年于我院内分泌门诊及住院部诊治的73例初诊2型糖尿病患者纳入研究.根据数字随机法分为两组,诺和灵组37例(予格华止口服及诺和灵30R皮下注射)和亚莫利组36例(予格华止和亚莫利口服).测定两组患者治疗前后的空腹血糖,餐后2h血糖,0和120的胰岛素水平和C肽水平.结果:(1)与治疗前相比,诺和灵组和亚莫利组的空腹血糖和餐后2h血糖都有显著下降,0和120胰岛素水平和C肽水平则显著升高(p＜0.05).(2)治疗3个月后两组比较,空腹血糖和餐后2h血糖没有显著性差异;0和120胰岛素和C肽水平均显示诺和灵组显著高(p＜0.05).结论:早期使用胰岛素治疗可使2型糖尿病患者胰岛β细胞获益.
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