论文部分内容阅读
肾性骨营养不良简称肾性骨病。近年来由于肾功能检测手段及治疗上的进展,特别是透析疗法和肾脏移植手术的增加,使患者生命延长。因而本病发生率不断增多。本病系长期慢性肾小球或肾小管病变等引起慢性肾功能衰竭,酸中毒,钙磷镁等矿物代谢紊乱,以及维生素D代谢障碍的一种代谢性骨病。它可发生在肾脏病程的任何阶段,常有骨质疏松,骨软化,肾性佝偻病,纤维囊性骨炎,骨硬化,软组织钙化,骨骺滑脱,骨畸形和病理性骨折等表现,且与肾功能程度,血液酸硷度,电解质或其它微量元素变化,甲状旁腺激素(PTH),降钙素(CT),活性维生素D如1α羟维生素D(1αOHD),1.25二羟维生素D(1.25(OH)_2D)等代谢有关。
Renal osteodystrophy referred to as renal osteodystrophy. In recent years, due to renal function tests and treatment progress, especially dialysis therapy and kidney transplantation increased, so that patients with prolonged life. Therefore, the incidence of this disease continues to increase. The disease is a long-term chronic glomerular or tubular lesions caused by chronic renal failure, acidosis, calcium and magnesium and other mineral metabolic disorders, and metabolic disorders of vitamin D, a metabolic bone disease. It can occur at any stage of the kidney disease, often osteoporosis, osteomalacia, renal rickets, fibrocystic osteitis, osteosclerosis, soft tissue calcification, epiphyseal slippage, bone deformity and pathological fracture performance, and kidney and kidney Functional level, blood pH, electrolyte or other trace element changes, parathyroid hormone (PTH), calcitonin (CT), active vitamin D such as 1α hydroxyvitamin D (1αOHD), 1.25 dihydroxyvitamin D OH) _2D) and other metabolic related.