超低能量(VLCD)疗法开发的历史1.绝食疗法减肥就是要达到能量负平衡,所以摄取能量为零,是最有效的减肥方法。针对不接受饮食限制的病例,Bloom 于1959年引入VLCD 疗法。这种:疗法无痛苦,可以较长时间耐受,由于消耗能量得到了意外的减肥效果,他认为,短期绝食治疗肥胖是有效的。Duncan 报告了107例肥胖者5～14日绝食后,再进行1～2日间断绝食;其减肥效果,绝食疗法开始的第51天,平均减重22.6公斤,1～32个月后40%的人恢复原体重;43%不变,17% History of ultra-low energy (VLCD) therapy development 1. Fasting therapy Weight loss is to achieve negative energy balance, so the energy intake is zero, is the most effective way to lose weight. In 1959, Bloom introduced VLCD for patients who did not receive dietary restrictions. This: therapies are painless and tolerable for longer periods of time, resulting in unexpected weight loss due to energy expenditure, and he believes short-term hunger strike to treat obesity is effective. Duncan reported 107 obese 5 to 14 after a hunger strike, and then for 1 to 2 days of intermittent hunger; the weight loss effect, the first 51 days of hunger strike therapy, the average weight loss of 22.6 kg, 1 to 32 months after 40% of People restore the original weight; 43% unchanged, 17%