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目的观察奥美拉唑联合克拉霉素治疗胃溃疡的疗效。方法 86例患者随机分为实验组和对照组。实验组患者46例,给予奥美拉唑联合克拉霉素口服治疗;对照组患者40例单纯予以奥美拉唑口服治疗。疗程完成后,观察并比较两组患者的临床疗效。结果实验组患者的临床总有效率为76.1%,对照组的临床总有效率为52.5%,两组总有效率差异有统计学意义(P<0.05)。实验组患者疗效显著优于对照组患者。两组患者在治疗期间均未出现严重的不良反应。结论奥美拉唑联合克拉霉素治疗胃溃疡是一种理想的治疗方案。
Objective To observe the efficacy of omeprazole combined with clarithromycin in the treatment of gastric ulcer. Methods 86 patients were randomly divided into experimental group and control group. Forty-six patients in the experimental group were orally treated with omeprazole and clarithromycin, and 40 patients in the control group were orally treated with omeprazole alone. After the completion of treatment, the clinical efficacy was observed and compared between the two groups. Results The total clinical effective rate was 76.1% in the experimental group and 52.5% in the control group. There was significant difference between the two groups in total effective rate (P <0.05). The efficacy of the experimental group was significantly better than that of the control group. Two groups of patients during the treatment did not appear serious adverse reactions. Conclusion omeprazole combined with clarithromycin in the treatment of gastric ulcer is an ideal treatment.