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目的探讨分析经鼻间歇正压通气(NIPPV)在新生儿呼吸衰竭拔管后的临床效果。方法 79例新生儿呼吸衰竭机械通气患儿,随机分成研究组41例行NIPPV治疗和对照组38例行鼻塞持续正压通气(NCPAP)治疗。比较两组患儿的住院时间、上机时间、血气分析结果。结果研究组患儿拔管后无创通气6、12 h的血气分析结果显著高于对照组,差异具有统计学意义(P<0.05);研究组患儿的住院时间、机械通气时间明显低于对照组,差异具有统计学意义(P<0.05)。结论采用经鼻间歇正压通气在新生儿呼吸衰竭拔管后呼吸支持上具有显著的临床疗效。
Objective To investigate the clinical effect of nasal intermittent positive pressure ventilation (NIPPV) after extubation of neonatal respiratory failure. Methods A total of 79 neonates with respiratory failure and mechanical ventilation were randomly divided into study group (41 cases) treated with NIPPV and control group (38 cases) treated with nasal continuous positive airway pressure (NCPAP). The hospitalization time, the time on the machine and the results of blood gas analysis were compared between the two groups. Results The blood gas analysis results of non-invasive ventilation in study group 6 and 12 h after extubation were significantly higher than those in control group (P <0.05). The hospitalization time and mechanical ventilation time in study group were significantly lower than those in control group Group, the difference was statistically significant (P <0.05). Conclusion The use of nasal intermittent positive pressure ventilation in respiratory failure after extubation of respiratory support has a significant clinical effect.