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本文报告1989年1月~1991年7月收治病毒性肝炎并发十二指肠溃疡12例患者,全部病例均呈乙型肝炎病毒标志物阳性。其临床表现如下:①全部病例均经胃肠X线钡餐造影或内镜检查证实;②不同类型的病毒性肝炎均可发生十二指肠溃疡,尤以慢性活动性肝炎及急性肝炎为多见;③仅1/3的患者有典型的消化性溃疡表现;④十二指肠溃疡不仅可发生于肝炎的急性期,也可见于恢复期;⑤十二指肠溃疡可使病毒性肝炎患者病情加重,⑥十二指肠溃疡和食道静脉曲张均是肝炎后肝硬化引起胃肠道出血的原因。作者认为消化性溃疡可能是病毒性肝炎的肝外表现之一,对肝炎后肝硬化发生胃肠道出血时,并用气囊填塞及甲氰咪呱类药物治疗是必要的。
This article reports from January 1989 to July 1991 were treated with viral hepatitis complicated by duodenal ulcer in 12 patients, all cases were positive for hepatitis B virus markers. The clinical manifestations are as follows: ① All cases were confirmed by gastrointestinal X-ray barium meal or endoscopy confirmed; ② different types of viral hepatitis can occur duodenal ulcers, especially chronic active hepatitis and acute hepatitis are more common ; ③ only 1/3 of patients with typical peptic ulcer performance; ④ duodenal ulcer can occur not only in the acute phase of hepatitis can also be found in recovery; ⑤ duodenal ulcer patients with viral hepatitis can make the disease Aggravating, ⑥ duodenal ulcer and esophageal varices are the cause of post-hepatitis cirrhosis gastrointestinal bleeding. The authors believe that peptic ulcer disease may be one of the extrahepatic manifestations of viral hepatitis. Gastrointestinal bleeding and post-hepatitis C cirrhosis are necessary for the treatment of peptic ulcer disease.