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目的对神经节苷脂治疗重症手足口病伴病毒性脑炎患儿的药物作用及效果进行分析与探讨。方法以我院收治的40例重症手足口病伴病毒性脑炎患儿为研究对象,随机分成两组。对照组采用常规措施进行治疗,实验组则在常规治疗基础上增加神经节苷脂的治疗。对两组患儿临床疗效及症状改善时间进行观察比较。结果实验组临床总有效率明显高于对照组,临床症状改善时间明显短于对照组,差异存在统计学意义,P<0.05。结论采用神经节苷脂对重症手足口病伴病毒性脑炎患儿具有显著的治疗效果,能有效改善临床症状,值得临床推广与普及。
Objective To analyze and discuss the effect of gangliosides on children with severe hand-foot-mouth disease complicated with viral encephalitis. Methods Forty cases of severe HFMD with viral encephalitis admitted to our hospital were randomly divided into two groups. The control group was treated with routine measures, while the experimental group was treated with ganglioside on the basis of routine treatment. The clinical efficacy and symptom improvement time in two groups were observed and compared. Results The total clinical effective rate in the experimental group was significantly higher than that in the control group, and the clinical symptom improvement time was significantly shorter than that in the control group, with statistical significance (P <0.05). Conclusion Gangliosides have significant therapeutic effect on severe hand-foot-mouth disease in children with viral encephalitis, which can effectively improve clinical symptoms and deserve clinical promotion and popularization.