目的 :探讨对虾白斑症的病程及病症特点 .方法 :对健康斑节对虾进行人工感染 ,同时用套式PCR检测感染后斑节对虾血液中病毒核酸的相对含量 .结果 :斑节对虾感染白斑症病毒后 ,依次表现出厌食、不活动、体色变红、甲壳出现白斑、反应迟钝直至侧卧死亡 ;濒死对虾的典型症状为空胃、红体、甲壳白斑、甲壳下水肿及甲壳易剥离 ;感染对虾出现拒食后 ,其血液中白斑症病毒 (WSSV)DNA的相对含量急剧增加 .结论 :甲壳下水肿和甲壳易剥离可能是斑节对虾白斑症的特征性病症 ;对虾外观病症的出现可能与对虾体内病毒的增殖相关联 Objective: To investigate the course and symptoms of white spot disease (WSSW) .Methods: Artificial infection of healthy Penaeus monodon was carried out, and the relative content of viral nucleic acid in Penaeus monodon was detected by nested PCR.Results: Virus, followed by anorexia, inactivity, body color turns red, carapace appear white, unresponsive until the lateral death; typical symptoms of dying shrimp empty stomach, red body, crustacean, subcapsular edema and carapace easy to peel ; The relative content of white blood streak virus (WSSV) DNA in infected shrimp increased sharply after antifeeding.Conclusion: The subcapsular edema and carapace peel may be the characteristic symptoms of white spot disease of Penaeus monodon Associated with the proliferation of viruses in shrimp