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目的:探讨结直肠癌卵巢转移患者的临床病理特征和预后。方法:回顾性分析2010—2015年中国医学科学院肿瘤医院收治的122例结直肠癌卵巢转移患者的临床病理资料，生存分析采用Kaplan-Maier法，预后影响因素分析采用Log rank检验和Cox比例风险模型。结果:122例结直肠癌卵巢转移患者的中位总生存时间(OS)为19.7个月，1、3、5年生存率分别为72.1%、24.7%和9.9%。122例患者中，行卵巢切除99例(81.1%)。行卵巢切除患者的中位OS(21.9个月)高于未行卵巢切除的患者(10.3个月，n P<0.01)。单纯卵巢转移、原发肿瘤切除和卵巢转移灶切除均与患者的总生存有关(均n P<0.01)；原发肿瘤切除和卵巢转移灶切除为影响患者总生存的独立因素(均n P<0.01)。n 结论:结直肠癌卵巢转移患者接受积极的手术治疗，包括原发肿瘤切除术和卵巢转移灶切除术，可能获得生存改善。“,”Objective:To explore the clinicopathological characteristics and prognosis of patients with ovarian metastases from colorectal cancer.Methods:A total of 122 female patients with ovarian metastases from colorectal cancer underwent treatment in Cancer Hospital, Chinese Academy of Medical Sciences between 2010 and 2015 were recruited. The clinicopathological features, treatment details and survival data of these patients were retrospectively analyzed. Kaplan-Maier method was used for survival analysis, log rank test and Cox proportional hazards model were used for prognostic factor analysis.Results:The median overall survival (OS) was 19.7 months. The 1-year, 3-years and 5-years OS rates were 72.1%, 24.7% and 9.9%, respectively. A total of 99 (81.1%) patients underwent oophorectomy. The median OS of patients who underwent oophorectomy was 21.9 months, significantly longer than 10.3 months of patients without oophorectomy (n P<0.01). Ovary as the only site of metastasis, primary tumor resection, and oophorectomy were associated with improved survival (alln P<0.01). Primary tumor resection and oophorectomy were independent prognostic factors for OS (bothn P<0.01).n Conclusion:Patients with ovarian metastases from colorectal cancer might acquire a survival benefit from surgical resection of the primary tumor and ovaries.