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目的探讨阻塞性睡眠呼吸暂停综合征(OSAS)与心肌缺血及心律失常的相关性及危险性。方法对90例睡眠呼吸暂停综合征患者进行多导睡眠图和12导动态心电图同步监测,观察ST-T改变和期前收缩发生情况。结果OSAS患者心肌缺血总发生率为32.2%,其中重度OSAS组发生率为59.4%,中度OSAS组发生率为15.8%,轻度OSAS组发生率为20%,三组与对照组比较差异有统计学意义(P<0.01),重度与轻、中度组比较差异有统计学意义(P<0.05)。OSAS组室性期前收缩的发生率为67.7%,发生次数明显高于对照组,两组比较差异有统计学意义(P<0.05),重度OSAS组与轻、中度OSAS组比较差异有统计学意义(P<0.05)。室上性期前收缩发生次数及发生率与对照组比较,两组差异无统计学意义(P>0.05)。结论睡眠呼吸暂停综合征与心肌缺血及心律失常有较强相关性,是导致心血管疾病危险因素之一。
Objective To investigate the association and risk of obstructive sleep apnea syndrome (OSAS) with myocardial ischemia and arrhythmia. Methods Ninety patients with sleep apnea syndrome were monitored by polysomnography and 12-lead ambulatory electrocardiogram to observe the changes of ST-T and the occurrence of premature contractions. Results The total incidence of ischemic myocarditis in OSAS patients was 32.2%, of which 59.4% in severe OSAS group, 15.8% in moderate OSAS group and 20% in mild OSAS group. There was significant difference between the three groups and the control group There was statistical significance (P <0.01). There was significant difference between severe and mild and moderate groups (P <0.05). The incidence of premature ventricular contractions in OSAS group was 67.7%, the frequency of occurrence was significantly higher than that of the control group, the difference was statistically significant (P <0.05), the difference was statistically significant between severe OSAS group and mild to moderate OSAS group Significance (P <0.05). The incidence and incidence of supraventricular premature contractions compared with the control group, there was no significant difference between the two groups (P> 0.05). Conclusion Sleep apnea syndrome has a strong correlation with myocardial ischemia and arrhythmia, which is one of the risk factors of cardiovascular disease.