目的 :探讨胃肠道间质瘤的临床病理及免疫组化特点和诊断标准。方法 :对 32例胃肠道间质瘤进行常规病理检查及免疫组化染色。结果 :胃肠道间质瘤由梭形细胞和上皮样细胞组成 ,大多数病例CD1 1 7和CD34标记阳性。结论 :胃肠道间质瘤是胃肠道常见的非上皮性肿瘤 ,缺乏定向分化。CD1 1 7、CD34标记阳性对胃肠道间质瘤的诊断具有重要的价值 Objective: To investigate the clinicopathological features, immunohistochemical characteristics and diagnostic criteria of gastrointestinal stromal tumors. Methods: Thirty-two gastrointestinal stromal tumors were examined by routine pathology and immunohistochemistry. Results: Gastrointestinal stromal tumors consisted of spindle cells and epithelial cells, most of which were positive for CD117 and CD34. Conclusion: Gastrointestinal stromal tumor is a common non-epithelial tumor of the gastrointestinal tract and lacks directional differentiation. CD1 1 7, CD34 positive for the diagnosis of gastrointestinal stromal tumors of great value