超声心动图对尿毒症血透患者并发肺动脉高压的临床研究

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目的研究应用超声心动图诊断尿毒症血液透析(血透)患者并发肺动脉高压的临床效果。方法 80例尿毒症实施血液透析患者作为研究对象,应用超声心动图对患者的肺动脉压进行评估,将存在肺动脉高压患者定义为观察组,未出现肺动脉高压患者定义为对照组。比较两组患者的一般资料及超声心动图检测结果。结果 80例患者中,肺动脉高压17例、占患者总数的21.25%(观察组),正常肺动脉压63例、占患者总数的78.75%(对照组)。两组患者的年龄、性别对比,差异均无统计学意义(t=0.0712,χ~2=0.0085,P>0.05);观察组患者透析时间长于对照组,收缩压及舒张压均高于对照组,差异均具有统计学意义(t=2.3238、2.0205、2.1278,P<0.05)。两组患者超声心动图检测结果中每搏输出量、左心室射血分数、心输出量对比,差异均无统计学意义(t=0.2960、0.7413、0.1219,P>0.05);观察组患者的收缩期肺动脉压显著高于对照组,差异具有统计学意义(t=10.6885,P<0.05)。结论尿毒症血液透析患者仅少部分存在肺动脉高压情况,患者的心输出量、每搏输出量、左心室射血分数等超声心动图检测指标与收缩期肺动脉压增高无明显的关系,故尿毒症血液透析患者并发肺动脉高压的影响因素还有待临床实验去发现研究。 Objective To study the clinical effect of using echocardiography in the diagnosis of pulmonary hypertension in patients with hemodialysis (hemodialysis). Methods Eighty patients with hemodialysis who underwent hemodialysis were enrolled in this study. Echocardiography was used to evaluate pulmonary hypertension. Patients with pulmonary hypertension were defined as observation group and those without pulmonary hypertension were defined as control group. General data and echocardiographic results were compared between the two groups. Results Among the 80 patients, 17 cases were pulmonary hypertension, accounting for 21.25% of the total (observation group) and 63 cases of normal pulmonary hypertension (78.75% of the total) (control group). There was no significant difference in age and sex between the two groups (t = 0.0712, χ ~ 2 = 0.0085, P> 0.05). The dialysis duration in the observation group was longer than that in the control group, and the systolic and diastolic blood pressures were higher in the observation group than in the control group , The differences were statistically significant (t = 2.3238,2.0205,2.1278, P <0.05). Echocardiographic results of the two groups of stroke volume, left ventricular ejection fraction, cardiac output, the difference was not statistically significant (t = 0.2960,0.7413,0.1219, P> 0.05); observation group patients with contraction Pulmonary arterial pressure was significantly higher than the control group, the difference was statistically significant (t = 10.6885, P <0.05). Conclusion Only a small part of patients with uremia hemodialysis pulmonary hypertension, the patient’s cardiac output, stroke volume, left ventricular ejection fraction and other indicators of echocardiography and systolic pulmonary hypertension did not show a significant relationship, so uremia Factors affecting hemodialysis patients complicated with pulmonary hypertension have yet to be discovered in clinical trials.
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